The best introduction to Cuenca is simple: start walking. The historic centre is full of colonial buildings, cobbled streets, wooden balconies, churches, small plazas, local shops and cafés.
Begin around Parque Calderón, the main square and natural heart of the city. From here, you can easily visit the main cathedrals, the flower market, museums and several attractive streets.
Do the historic centre slowly. Cuenca is not about racing through landmarks — it is about atmosphere.